General Summary

  • Trade name: Januvia
  • Generic name: Sitagliptin
  • Drug class: DPP-4 Inhibitors
  • Manufacturer: Merck & Co, Inc.

What is Januvia?

Januvia is an oral gliptin medication that is used to lower blood glucose levels in people with type 2 diabetes. It works by stopping the DPP-4 enzyme that destroys GLP and GIP hormones, meaning both can function more effectively. Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are released into the body by the intestine and affect blood glucose levels. When more of these hormones are released blood sugar levels are reduced.

Who Can Take Januvia?

People who have type 2 diabetes are usually prescribed Januvia, to be taken alongside a healthy diet and regular exercise. Additionally, Januvia is usually taken alongside other diabetes medications such as:

Side Effects

There are some common side effects that are related to Januvia and are as follows:

  • Infections of the upper respiratory tract
  • Headaches

The following side effects are more infrequent but can still occur:

  • Abdominal pain
  • Nausea
  • Diarrhoea